Dosage and Administration of Pletal (Cilostazol)

Introduction

Cilostazol is a medication used under the brand name Pletal for the treatment of intermittent claudication and secondary prevention in certain patients․ Its mechanism of action involves phosphodiesterase (PDE) III inhibition to increase cAMP levels․

Overview of Cilostazol (Pletal)

Cilostazol‚ marketed as Pletal‚ is primarily used for the treatment of intermittent claudication and secondary prevention in certain patients․ It functions by inhibiting phosphodiesterase (PDE) III‚ leading to increased cAMP levels․ Commonly available in 50 mg triangular and 100 mg round tablets for oral administration‚ Cilostazol improves walking distance in peripheral vascular disease by promoting vasodilation and antiplatelet activity․

Recommended Dosage

Therapeutic dosing of Cilostazol typically involves a regimen of 100 mg orally twice daily․ The medication is usually taken without food‚ approximately 30 minutes before or 2 hours after meals․ Adjustments in dosage may be necessary based on individual patient characteristics․

Therapeutic Dosing of Cilostazol

Cilostazol is typically recommended to be taken as a 100 mg oral dose twice daily․ The medication is advised to be consumed without food‚ either 30 minutes before or 2 hours after meals․ Dosing adjustments might be required in certain cases based on individual patient response and medical considerations․

Dosage Forms

Cilostazol (Pletal) tablets are available in two strengths⁚ 50 mg triangular and 100 mg round tablets for oral administration․ The tablets contain inactive ingredients in addition to the active compound․

Available Tablet Strengths

Cilostazol (Pletal) tablets come in two strengths⁚ 50 mg triangular and 100 mg round tablets for oral administration․ Each tablet contains inactive ingredients along with the active compound․ These different strengths accommodate individualized dosage requirements for patients․

Administration Guidelines

Proper way to take Cilostazol involves oral administration without food‚ usually 30 minutes before or 2 hours after meals․ The dosing regimen typically consists of 100 mg taken twice daily‚ with adjustments based on individual response․

Proper Way to Take Cilostazol

Patients are advised to take Cilostazol orally without food‚ typically twice daily at least 30 minutes before or 2 hours after breakfast and dinner․ The dosage regimen usually consists of 100 mg per dose‚ with adjustments based on individual needs and response․

Dosage Adjustment

Considerations for dose modification may be applied to cilostazol based on individual responses and patient-specific factors․ The typical dosage regimen consists of 100 mg taken twice daily‚ with potential adjustments as needed․

Considerations for Dose Modification

When it comes to dose adjustments for Cilostazol‚ individual responses and specific patient factors play a crucial role․ The standard dosing typically involves 100 mg taken twice daily‚ with the potential for modifications as warranted by the patient’s condition․

Drug Interactions

The U․S․ Food and Drug Administration identifies potential interactions affecting Cilostazol’s dosage with drugs like macrolide antibiotics‚ diltiazem‚ and others that impact CYP3A4 and CYP2C19 activity․

Potential Interactions Affecting Dosage

Interactions affecting the dosage of Cilostazol involve drugs such as macrolide antibiotics‚ diltiazem‚ and others known to impact CYP3A4 and CYP2C19 enzyme activity․ These interactions can alter the clearance and efficacy of Cilostazol‚ necessitating dose adjustments or careful monitoring․

Side Effects

Common adverse reactions to Cilostazol may include diarrhea‚ headache‚ or fast heartbeats․ It is essential for patients to be aware of these potential side effects and consult a healthcare provider for further guidance․

Common Adverse Reactions to Cilostazol

Common adverse reactions to Cilostazol may include diarrhea‚ headache‚ or fast heartbeats․ It is vital for patients to be aware of these potential side effects and consult healthcare professionals for further guidance if needed․

Patient Information

Patients taking Cilostazol should be aware of potential side effects like diarrhea‚ headache‚ and fast heartbeats․ It is crucial to consult healthcare providers promptly for guidance and monitoring․

Important Instructions for Patients Taking Cilostazol

Patients taking Cilostazol should be cautious of potential side effects such as diarrhea‚ headache‚ and fast heartbeats․ If experiencing any severe or prolonged adverse effects‚ it is advised to seek immediate medical advice․