Overview of Calan SR
Calan SR‚ also known as Verapamil‚ is a medication commonly used to treat high blood pressure. It belongs to a class of drugs called calcium channel blockers. By lowering high blood pressure‚ Calan SR helps prevent strokes‚ heart attacks‚ and kidney problems. It is essential to understand potential drug interactions‚ side effects‚ dosages‚ and precautions when using Calan SR. Always consult with your healthcare provider to ensure the safe and effective use of this medication.
Common Drug Interactions
When using Calan SR (Verapamil)‚ it is crucial to be aware of potential drug interactions to ensure the safe and effective use of this medication. Verapamil can interact with a wide range of medications‚ affecting your blood levels of verapamil and potentially causing side effects or reducing its effectiveness. It is important to inform your healthcare provider about all the medications you are currently taking‚ including over-the-counter drugs‚ vitamins‚ and supplements. Some commonly reported interactions with Calan SR include interactions with verapamil‚ beta blockers‚ simvastatin‚ and grapefruit juice. Always consult with your doctor to avoid any adverse effects and optimize the benefits of your treatment.
Verapamil Metabolism and Interactions
Verapamil‚ the active ingredient in Calan SR‚ undergoes metabolism in the body primarily through cytochrome P450 enzymes‚ including CYP3A4‚ CYP1A2‚ CYP2C8‚ CYP2C9‚ and CYP2C18. These enzymes play a crucial role in how verapamil is processed and eliminated from the body. Understanding the metabolism of verapamil is essential as it can impact its efficacy and potential interactions with other medications.
Cytochrome Inducers/Inhibitors Interaction
Verapamil‚ the active ingredient in Calan SR‚ is metabolized by cytochrome P450 enzymes such as CYP3A4‚ CYP1A2‚ CYP2C8‚ CYP2C9‚ and CYP2C18. These enzymes play a significant role in how verapamil is processed in the body and can be affected by drugs that induce or inhibit these enzymes. Understanding these interactions is crucial as they can impact the effectiveness and safety of verapamil when used in combination with other medications that affect these cytochrome enzymes.