Diclegis: FDA Approval Information

Overview of Diclegis FDA Approval Information

The FDA approved Diclegis, a combination of doxylamine succinate and pyridoxine hydrochloride, in 2013; It is indicated for the treatment of nausea and vomiting of pregnancy in women who do not respond to conservative management.​ Diclegis is now the only FDA-approved prescription medicine for this condition and provides relief when diet and lifestyle changes are ineffective. The most common side effect of Diclegis is drowsiness.​ The medication underwent extensive clinical trials before receiving FDA approval.​

Diclegis FDA Approval History

In April 2013, the US Food and Drug Administration (FDA) approved doxylamine succinate 10 mg and pyridoxine hydrochloride (a vitamin B6 analog) 10 mg as a delayed-release combination pill called Diclegis for the treatment of nausea and vomiting of pregnancy (NVP).​ Diclegis is currently the only medication that is FDA-approved for the indication of NVP;

Indications and Usage

Diclegis is a delayed-release tablet containing a combination of doxylamine, an antihistamine, and pyridoxine, a form of vitamin B6.​ This medication is specifically indicated for the treatment of nausea and vomiting of pregnancy (NVP) when conservative management methods, such as dietary and lifestyle changes, do not provide relief.​ Pregnant women can consider Diclegis as an option to alleviate these symptoms.​ Always consult with a healthcare provider before starting any new medication.​

Composition and Dosage

Diclegis is a delayed-release tablet that combines doxylamine succinate, an antihistamine, and pyridoxine hydrochloride, a form of vitamin B6.​ Each tablet contains 10 mg of doxylamine succinate and 10 mg of pyridoxine hydrochloride.​ The recommended dosage typically involves taking one tablet at bedtime, and if necessary, one additional tablet in the morning.​ It is crucial to follow the dosage instructions provided by a healthcare professional to ensure proper usage and effectiveness of the medication.​

Study Participants and Clinical Trials

Diclegis underwent clinical trials with study participants who were pregnant women experiencing nausea and vomiting of pregnancy (NVP).​ These participants were between seven and fourteen weeks pregnant.​ The trials aimed to assess the effectiveness and safety of Diclegis in providing relief from NVP symptoms when conservative management methods were not effective. The FDA approval of Diclegis was based on the results of these trials.​

Safety Information and Side Effects

When taking Diclegis, it’s important to be aware of potential side effects, with drowsiness being the most common.​ If you experience any unusual or severe side effects while using Diclegis, it is essential to contact your healthcare provider promptly. It’s advisable not to operate heavy machinery or drive until you know how Diclegis affects you. Always follow the safety guidelines provided by your healthcare professional to ensure the proper and safe use of Diclegis.​

10 responses to “Diclegis: FDA Approval Information”

  1. Sophia Avatar
    Sophia

    Diclegis seems to be a promising option for pregnant women experiencing nausea and vomiting who have not found relief through other methods. It

  2. Lily Avatar
    Lily

    The FDA approval of Diclegis underscores the importance of addressing the unique healthcare needs of pregnant women. While it can be effective in providing relief, it

  3. Oliver Avatar
  4. Nora Avatar
    Nora

    While Diclegis may be the only FDA-approved prescription medicine for nausea and vomiting of pregnancy, it

  5. Grace Avatar
    Grace

    Diclegis offers hope for pregnant women dealing with persistent nausea and vomiting that do not improve with lifestyle changes alone. It

  6. Ethan Avatar
    Ethan

    The approval of Diclegis by the FDA in 2013 brought relief to many pregnant women struggling with severe nausea and vomiting. It

  7. Owen Avatar
    Owen

    For pregnant women seeking relief from nausea and vomiting that disrupt daily life, Diclegis represents a specialized treatment option worth exploring. Prioritize open communication with your healthcare provider to determine if this medication aligns with your health goals.

  8. Leo Avatar
    Leo

    Pregnant women considering Diclegis as a treatment option should weigh the benefits of symptom relief against the risk of drowsiness. It

  9. Max Avatar
    Max

    When considering Diclegis for the management of nausea and vomiting during pregnancy, it

  10. Ava Avatar
    Ava

    For pregnant women who have exhausted other options for managing nausea and vomiting, Diclegis could offer a much-needed solution. However, it